Disappointingly little evidence

Little evidence for sympatric speciation in island birds.

It has been suggested that the presence of sister species in small circumscribed areas, such as isolated lakes or islands, might imply that these species originated sympatrically. To investigate this possibility in birds, we searched for endemic, congeneric species on isolated islands in the ocean. Among 46 islands and small archipelagos chosen because they contain at least one species of endem...

Little languages: little maintenance?

So-called little, or domain-specific languages (DSLs), have the potential to make software maintenance simpler: domain-experts can directly use the DSL to make required routine modifications. At the negative side, however, more substantial changes may become more difficult: such changes may involve altering the domain-specific language. This will require compiler technology knowledge, which not...

Little evidence for developmental plasticity of adult hematopoietic stem cells.

To rigorously test the in vivo cell fate specificity of bone marrow (BM) hematopoietic stem cells (HSCs), we generated chimeric animals by transplantation of a single green fluorescent protein (GFP)-marked HSC into lethally irradiated nontransgenic recipients. Single HSCs robustly reconstituted peripheral blood leukocytes in these animals, but did not contribute appreciably to nonhematopoietic ...

A Little More Evidence from the Time Series

Delayed breeding in Little Penguins – evidence of climate change?

In the past few years there has been a resurgence of interest in the possibility of detecting climate change using natural systems (see, for example, Crick and Sparks 1999; Sparks and Menzel 2002; Hughes 2003; Parmesan and Yohe 2003; Root et al. 2003). The study of recurring natural (or biological) events, often in relation to climate, is known as phenology. These studies typically record event...